What would you do with 10kbp reads?
So, anyhow, I'm trying to think two steps ahead. 2010 is supposed to be the year that Pacific Biosciences (and other companies) release the next generation of sequencing technologies - which will undoubtedly be longer than 1k. (I seem to recall hearing that PacBio has 10k+ reads.- UPDATE: I found a reference.) So to heck with 1kbp reads, this raises the real question: What would you do with a 10,000bp read? And, equally important, how do you work with a 10kbp read?
- What software do you have now that can deal with 10k reads?
- Will you align or assemble with a 10k read?
- What experiments will you be able to do with a 10k read?
So, what do you think?